Monday
August 29th 2022
Welcome and opening lectures
Chairs:
Enza Maria Valente
Riccardo Bellazzi
16.30 – 17.00
Opening remarks
Enza Maria Valente, Riccardo Bellazzi (Pavia, Italy)
17.00 – 17.30
Lecture 1 – NGS in prenatal diagnosis
Isabel Filges (Basel, Switzerland)
17.30 – 18.00
Lecture 2 – Long-read sequencing and future perspectives in clinical setting
Luciano Xumerle (Verona, Italy)
18.00 – 18.30
Lecture 3 – Proteomics in clinical practice
Daniel L. Minor (San Francisco, United States)
18.30 – 19.00
Lecture 4 – Omics in the clinics: how Italy is facing this challenge
Vincenzo Nigro (Naples, Italy)
19.00 – 21.00
Welcome cocktail and get together
Tuesday
August 30th 2022
Clinical Genomics – Coding Variants
Chair:
Francesco Lescai
9.00 – 9.30
Outline of school and brief round of introduction
Francesco Lescai (Pavia, Italy)
9.30 – 11.00
Digital (r)evolution in Medicine: the pervasive role of Bioinformatics
Francesco Lescai (Pavia, Italy)
11.00 – 11.30
Energy break
11.30 – 12.30
Interpretation of coding variants and instructive clinical cases
Marco Savarese (Helsinki, Finland)
12.30 – 13.00
Final Discussion
13.00 – 14.00
Lunch break
14.00 – 16.00
Interactive guided practice
Francesco Lescai, Edoardo Errichiello (Pavia, Italy) and Marco Savarese (Helsinki, Finland)
16.00 – 16.30
Energy break
16.30 – 18.00
Course challenge: focus groups work
18.00 – 18.30
PRESENTATION OF FOCUS GROUP WORK
Wednesday
August 31st 2022
Clinical Genomics – Cryptic Variants
Chair:
Elisa Giorgio
9.00 – 10.00
Beyond SNVs: tools to exploit CNVs
Romina D’Aurizio (Pisa, Italy)
10.00 – 11.00
Hands-on practice
Romina D’Aurizio (Pisa, Italy)
11.00 – 11.30
Energy break
11.30 – 12.30
Non-coding variants and instructive clinical cases
Malte Spielmann (Lübeck, Germany)
12.30 – 13.00
Final Discussion
13.00 – 14.00
Lunch break
14.00 – 16.00
Interactive guided practice
Elisa Giorgio (Pavia, Italy), Malte Spielmann (Lübeck, Germany) and Romina D’Aurizio (Pisa, Italy)
16.00 – 16.30
Energy break
16.30 – 18.00
Course challenge: focus groups work
18.00 – 18.30
PRESENTATION OF FOCUS GROUP WORK
Thursday
September 1st 2022
Clinical Transcriptomics
Chair:
Lorenzo Pasotti
9.00 – 10.00
Tools for transcript analysis and gene expression
Tjakko Van Ham (Rotterdam, The Netherlands)
10.00 – 11.00
Hands-on practice
Tjakko Van Ham (Rotterdam, The Netherlands)
11.00 – 11.30
Energy break
11.30 – 12.00
The Orange tool – bulk transcriptomics
Blaž Zupan (Ljubljana, Slovenia)
12.00 – 12.30
The Orange tool – single cell transcriptomics
Blaž Zupan (Ljubljana, Slovenia)
12.30 – 13.00
Final Discussion
13.00 – 14.00
Lunch break
14.00 – 16.00
Interactive guided practice
Blaž Zupan (Ljubljana, Slovenia), Lorenzo Pasotti (Pavia, Italy)
16.00 – 16.30
Energy break
16.30 – 18.00
Course challenge: focus groups work
18.00 – 18.30
PRESENTATION OF FOCUS GROUP WORK
19.30 – 20.00
Clinical Bioinformatics: data and knowledge integration for decision support
Riccardo Bellazzi (Pavia, Italy)
20.00 onwards
Clinical Bioinformatics Dinner
Friday
September 2nd 2022
Clinical Proteomics
Chair:
Marco Lolicato
9.00 – 10.00
What’s “Clinical Proteomics”? Tools and workflow
Marco Lolicato (Pavia, Italy)
10.00 – 11.00
“Computational Chemistry”: epitope prediction and vaccines
Giorgio Colombo (Pavia, Italy)
11.00 – 11.30
Energy break
11.30 – 12.00
Tools to exploit protein-protein interactions
Tommaso Mazza (Rome, Italy)
12.00 – 12.30
Tools to exploit molecular dynamics simulation
Tommaso Biagini (Rome, Italy)
12.30 – 13.00
Final Discussion
13.00 – 14.00
Lunch break
14.00 – 16.00
Interactive guided practice
Tommaso Mazza and Tommaso Biagini (Rome, Italy)
16.00 – 16.30
Energy break
16.30 – 18.00
Course challenge: focus groups work
18.00 – 18.30
PRESENTATION OF FOCUS GROUP WORK
18.30 – 19.00
Prizes and conclusive remarks